Lyme Disease
First made reportable in New Jersey in 1981, Lyme disease
is a multi-systemic, inflammatory disorder caused by
the spirochete Borrelia burgdorferi that is
transmitted primarily through the bite of an infected
blacklegged tick, known more familiarly as the deer
tick. About 50% of adult and 25% of nymphal blacklegged
ticks are infected with Lyme disease spirochetes. The
white-footed mouse, Peromyscus leucopus, and
Eastern chipmunk, Tamias striatus, are the
primary reservoir hosts. The infection is maintained
throughout the lifecycles of the tick, but transovarial
passage is infrequent.
Within 3-30 days following tick bite, Lyme disease is
often, but not always, characterized by a distinctive
skin lesion known as erythema migrans (EM),
which first appears as a red, raised area that expands
in size over time and may develop central clearing.
Single or multiple lesions are usually preceded or accompanied
by a variety of other symptoms, including headache,
fever, fatigue, malaise, joint pain, stiff neck, and
nausea. If untreated, neurological and cardiac symptoms
may develop within weeks or months of the appearance
of EM. Finally, individuals may develop swelling and
pain in the large joints. In both the early and advanced
phases of Lyme disease, symptoms are often recurrent
and may become chronic in untreated individuals. During
the last 5 years, an average of 2,750 confirmed Lyme
disease cases have been reported annually in New Jersey.
Lyme
Disease Fact Sheet